Publications

Yazdanbakhsh A., Dang K., Kuang K., Lian T., Liu X., Xie S., Zikopoulos B., Artificial intelligence networks combining histopathology and machine learning can extract axon pathology in autism spectrum disorder. bioRxiv [Preprint] DOI: 10.1101/2024.10.25.620308

Dias C., Chunhui Cai A., Sun L., Cabral K., Brownstein C.A., Rockowitz S., Walsh C.A. Cell-type-specific effects of autism-associated 15q duplication syndrome in the human brain. Am J Hum Genet. 2024 Aug 8;111, 1544-1558 PubMed

Pugsley K., Namipashaki A., Bellgrove M., Hawi Z. Evaluating the regulatory function of non-coding autism-associated single nucleotide polymorphisms on gene expression in human brain tissue. Autism Res. 2024 March 17; 3, 467-481 PubMed

Liu L., Qi X., Cheng S., Meng P., Yang X., Pan C., Zhang N., Chen Y., Li C., Zhang H., Zhang Z., Zhang J., Cheng B., Wen Y., Jia Y., Liu H., Zhang F. Epigenetic analysis suggests aberrant cerebellum brain aging in old-aged adults with autism spectrum disorder and schizophrenia. Mol. Psychiatry. 2023 November 28, 11, 4867-4876 PubMed

Perez Y.,  Velmeshev D., Wang L., White M., Siebert C., Baltazar J., Garcia Dutton N., Wang S., Haeussler M., Chamberlain S., Kriegstein A. Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism. bioRxiv [Preprint] DOI:10.1101/2023.09.22.559056

Wamsley B., Bicks L., Chang Y., Kawaguchi R., Quintero D., Grundman J., Liu J., Xiao S., Hawken N., Margolis M., Mazariegos S., Geschwind D. Molecular cascades and cell-type specific signatures in ASD revealed by single cell genomics. bioRxiv [Preprint] DOI: 10.1101/2023.03.10.530869

Zhang P., Omanska A., Ander B.P., Gandal M., Stamova B., Schumann C.M. Neuron-specific transcriptomic signatures indicate neuroinflammation and altered neuronal activity in ASD temporal cortex. Proc. Natl. Acad. Sci. U. S. A. 2023 March 7, 20, e2206758120 PubMed

Gandal M., Haney J.R., Wamsley B., Yap C.X., Parhami S., Emani P.S., Chang N., Chen G.T., Hoftman G.D., de Alba D., Ramaswami G., Hartl C.L., Bhattacharya A., Luo C., Jin T., Wang D., Kawaguchi R., Quintero D., Ou J., Wu Y.E., Parikshak N.N., Swarup V., Belgard T.G., Gerstein M., Pasaniuc B., Geschwind D. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature 2022 Nov. 2, 611, 532-539 PubMed

Berto S., Treacher A.H., Caglayan E., Luo D., Haney J.R., Gandal M., Geschwind D., Montillo A.A., Konopka G. Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder. Nat. Commun. 2022 June 9, 13, 3328 PubMed

Dias C.M., Talukdar M., Akula S.K., Walsh K., Walsh C., Glial dysregulation in human brain in fragile X-related disorders. bioRxiv [Preprint] DOI: 10.1101/2022.03.29.486195

Doan R.N., Miller M.B., Kim S.N., Rodin R.E., Ganz J., Bizzotto S., Morillo K.S., Huang A.Y., Digumarthy R., Zemmel Z., Walsh C.A. MIPP-Seq: Ultra-sensitive rapid detection and validation of low-frequency mosaic mutations. BMC Med. Genomics 2021 Feb 12; 14, 47 PubMed

Boyle L., Rao L., Kaur S., Fan X., Caroline Mebane, Laura Hamm, Thornton A., Ahrendsen J.T., Anderson M.P., Christodoulou J., Gennerich A., Shen Y., Chung W.K. Genotype and defects in microtubule-based motility correlate with clinical severity in KIF1A-associated neurological disorder. HGG Adv. 2021 Apr 8; 2, 10026 PubMed

Anderson M.P., Quinton R., Kelly K., Falzon A., Halladay A., Schumann C.M., Hof P.R., Tamminga C.A., Hare C.K., Amaral D.G. Autism BrainNet. Arch. Pathol. Lab. Med. 2021 Apr 1; 145, 494-501 PubMed

Amina S., Falcone C., Hong T., Wolf-Ochoa M.W., Vakilzadeh G., Allen E., Perez-Castro R., Kargar M., Noctor S., Martínez-Cerdeño V. Chandelier cartridge density is reduced in the prefrontal cortex in autism. Cereb. Cortex 2021 May 10; 31, 2944-2951 PubMed

Rodin R.E., Dou Y., Kwon M., Sherman M.A., D’Gama A.M., Doan R.N., Rento L.M., Girskis K.M., Bohrson C.L., Kim S.N., Nadig A., Luquette L.J., Gulhan D.C., Brain Somatic Mosaicism Network, Park P.J., Walsh C.A. The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. Nat. Neurosci. 2021 Feb 1; 24, 176-185 PubMed

Cioana M., Michalski B., Fahnestock M. Insulin-like growth factor and insulin-like growth factor receptor expression in human idiopathic autism fusiform gyrus tissue. Autism Res. 2020 June 01; 13, 897-907 PubMed

Hong T., Falcone C., Dufour B., Amina S., Perez Castro R., Regalado J., Pearson W., Noctor S.C., Martínez-Cerdeño V. GABA A Rα2 is decreased in the axon initial segment of pyramidal cells in specific areas of the prefrontal cortex in autism. Neuroscience 2020 June 15; 437, 76-86 PubMed

Huang A.Y., Li P., Rodin R.E., Kim S.N., Dou Y., Kenny C.J., Akula S.K., Hodge R.D., Bakken T.E., Miller J.A., Lein E.S., Park P.J., Lee E.A., Walsh C.A. Parallel rna and DNA analysis after deep sequencing (PRDD-seq) reveals cell type-specific lineage patterns in human brain. Proc. Natl. Acad. Sci. U S A 2020 June 23; 117, 13886-13895 PubMed

Sciara A.N., Beasley B., Crawford J.D., Anderson E.P., Carrasco T., Zheng S., Ordway G.A., Chandley M.J. Neuroinflammatory gene expression alterations in anterior cingulate cortical white and gray matter of males with autism spectrum disorder. Autism Res. 2020 June 1; 13, 870-884 PubMed

DiStasio M.M., Nagakura I., Nadler M.J., Anderson M.P. T lymphocytes and cytotoxic astrocyte blebs correlate across autism brains. Ann. Neurol. 2019 Dec 1; 86, 885-898 PubMed

Wong C.C.Y., Smith R.G., Hannon E., Ramaswami G., Parikshak N.N., Assary E., Troakes C., Poschmann J., Schalkwyk L.C., Sun W., Prabhakar S., Geschwind D.H., Mill J. Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue. Hum. Mol. Genet. 2019 July 1; 28, 2201-2211 PubMed

Amaral D.G., Anderson M.P., Ansorge O., Chance S., Hare C., Hof P.R., Miller M., Nagakura I., Pickett J., Schumann C., Tamminga C. Autism Brainnet: A network of postmortem brain banks established to facilitate autism research. Handb. Clin. Neurol. 2018 Jan 1; 150, 31-39 PubMed

Ariza J., Rogers H., Hashemi E., Noctor S.C., Martínez-Cerdeño V. The number of chandelier and basket cells are differentially decreased in prefrontal cortex in autism. Cereb. Cortex 2018 Feb 1; 28, 411-420 PubMed

Avino T.A., Barger N., Vargas M.V., Carlson E.L., Amaral D.G., Bauman M.D., Schumann C.M. Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism. Proc. Natl. Acad. Sci. U S A 2018 April 3; 115, 3710-3715 PubMed

Filipello F., Morini R., Corradini I., Zerbi V., Canzi A., Michalski B., Erreni M., Markicevic M., Starvaggi-Cucuzza C., Otero K., Piccio L., Cignarella F., Perrucci F., Tamborini M., Genua M., Rajendran L., Menna E., Vetrano S., Fahnestock M., Paolicelli R.C., Matteoli M. The microglial innate immune receptor TREM2 is required for synapse elimination and normal brain connectivity. Immunity 2018 May 15; 48, 979-991 PubMed

Lin C.Y., Chang K.W., Lin C.Y., Wu J.Y., Coon H., Huang P.H., Ho H.N., Akbarian S., Gau S.S., Huang H.S. Allele-specific expression in a family quartet with autism reveals mono-to-biallelic switch and novel transcriptional processes of autism susceptibility genes. Sci. Rep. 2018 March 9; 8, 4277 (2018) PubMed

Parras A., Anta H., Santos-Galindo M., Swarup V., Elorza A., Nieto-Gonzalez J.L., Pico S., Hernández I.H., Díaz-Hernández J.I., Belloc E., Rodolosse A., Parikshak N.N., Peñagarikano O., Fernández-Chacón R., Irimia M., Navarro P., Geschwind D.H., Mendez R., Lucas J.J. Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature 2018 Aug 1; 560, 441-446 PubMed

Shpyleva S., Melnyk S., Pavliv O., Pogribny I., James J.S. Overexpression of LINE-1 retrotransposons in autism brain. Mol. Neurobiol. 2018 Feb 1; 55, 1740-1749 PubMed

Soghomonian J.J., Zhang K., Reprakash S., Blatt G.J. Decreased parvalbumin mRNA levels in cerebellar Purkinje cells in autism. Autism Res. 2017 Nov 1; 10, 1787-1796 PubMed

Pagan C., Goubran-Botros H., Delorme R., Benabou M., Lemière N., Murray K., Amsellem F., Callebert J., Chaste P., Jamain S., Fauchereau F., Huguet G., Maronde E., Leboyer M., Launay J., Bourgeron T. Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders. Sci. Rep. 2017 May 18; 7, 2096 PubMed

Wegiel J., Flory M., Kaczmarski W., Brown W.T., Chadman K., Wisniewski T., Nowicki K., Kuchna I., Ma S.Y., Wegiel J. Partial agenesis and hypoplasia of the corpus callosum in idiopathic autism. J. Neuropathol. Exp. Neurol. 2017 Mar 1;76, 225-237 PubMed

Hashemi E., Ariza J., Rogers H., Noctor S.C., Martínez-Cerdeño V. The number of parvalbumin-expressing interneurons is decreased in the medial prefrontal cortex in autism. Cereb. Cortex. 2017 Mar 1; 27, 1931-1943 PubMed

Schumann C.M., Sharp F.R., Ander B.P., Stamova B. Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain. Mol. Autism. 2017 Feb 7; 8, 4 PubMed

Lee A.S., Azmitia E.C., Whitaker-Azmitia P.M. Developmental microglial priming in postmortem autism spectrum disorder temporal cortex. Brain Behav. Imm. 2017 May 1; 62, 193-202 PubMed.

Menassa D.A., Sloan C., Chance S.A. Primary olfactory cortex in autism and epilepsy: Increased glial cells in autism. Brain Pathol. 2017 Jul 1; 27, 437-448 PubMed

Ellis S.E., Gupta S., Moes A., West A.B., Arking D.E. Exaggerated CpH methylation in the autism-affected brain. Mol. Autism. 2017 Feb 17; 8, 6 PubMed

Zhubi A., Chen Y., Guidotti A., Grayson D.R. Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects. Int. J. Dev. Neurosci. 2017 Nov 1; 62, 63-72 PubMed

Dunaway K.W., Islam M.S., Coulson R.L., Lopez S.J., Vogel Ciernia A., Chu R.G., Yasui D.H., Pessah I.N., Lott P., Mordaunt C., Meguro-Horike M., Horike S.I., Korf I., LaSalle J.M. Cumulative impact of polychlorinated biphenyl and large chromosomal duplications on DNA methylation, chromatin, and expression of autism candidate genes. Cell Rep. 2016 Dec 13; 17, 3035-3048 PubMed

Parikshak N.N., Swarup V., Belgard T.G., Irimia M., Ramaswami G., Gandal M.J., Hartl C., Leppa V., Ubieta L.T., Huang J., Lowe J.K., Blencowe B.J., Horvath S., Geschwind D.H. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature 2016 Dec 15; 540, 423-427 PubMed

Karst A.T., Hutsler J.J. Two-dimensional analysis of the supragranular layers in autism spectrum disorder. Res. Autism Spectr. Disord. 2016 Dec 1; 32, 96-105 Article

Sun W., Poschmann J., Cruz-Herrera Del Rosario R., Parikshak N.N., Hajan H.S., Kumar V., Ramasamy R., Belgard T.G., Elanggovan B., Wong C.C., Mill J., Geschwind D.H., Prabhakar S. Histone acetylome-wide association study of autism spectrum disorder. Cell 2016 Nov 17; 167,1385-1397 PubMed

García-Cabezas M.Á., John Y.J., Barbas H., Zikopoulos B. Distinction of neurons, glia and endothelial cells in the cerebral cortex: An algorithm based on cytological features. Front. Neuroanat. 2016 Nov 1; 10, 107 PubMed

Wu Y.E., Parikshak N.N., Belgard T.G., Geschwind D.H. Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder. Nat. Neurosci. 2016 Nov 1; 19, 1463-1476 PubMed

Westmark C.J., Sokol D.K., Maloney B., Lahiri D.K. Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism. Mol. Psychiatry 2016 Oct 1; 21, 1333-1341 PubMed

Liu X., Han D., Somel M., Jiang X., Hu H., Guijarro P., Zhang N., Mitchell A., Halene T., Ely J.J., Sherwood C.C., Hof P.R., Qiu Z., Pääbo S., Akbarian S., Khaitovich P. Disruption of an evolutionarily novel synaptic expression pattern in autism. PLoS Biol. 2016 Sep 29; 14, e1002558 PubMed

Bakulski K.M., Halladay A., Hu V.W., Mill J., Fallin M.D. Epigenetic research in neuropsychiatric disorders: the “Tissue Issue”. Curr. Behav. Neurosci. Rep. 2016 Sep 1; 3, 264-274 PubMed

Hashemi E., Ariza J., Lechpammer M., Noctor S.C., Martínez-Cerdeño V. Abnormal white matter tracts resembling pencil fibers involving prefrontal cortex (Brodmann area 47) in autism: A case report. J. Med. Case Rep. 2016 Aug 26; 10, 237 PubMed

Ray B., Sokol D.K., Maloney B., Lahiri D.K. Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in autism spectrum disorder and fragile X syndrome plasma and brain tissue. Sci. Rep. 2016 May 23; 6, 26052 PubMed

Ellis S.E., Panitch R., West A.B., Arking D.E. Transcriptome analysis of cortical tissue reveals shared sets of downregulated genes in autism and schizophrenia. Transl. Psychiatry 2016 May 24; 6, e817 PubMed

Lintas C., Sacco R., Persico A.M. Differential methylation at the RELN gene promoter in temporal cortex from autistic and typically developing post-puberal subjects. J. Neurodev. Disord. 2016 Apr 29; 8,18 PubMed

Azmitia E.C., Saccomano Z.T., Alzoobaee M.F., Boldrini M., Whitaker-Azmitia P.M. Persistent angiogenesis in the autism brain: An immunocytochemical study of postmortem cortex, brainstem and cerebellum. J. Autism Dev. Disord. 2016 Apr 1; 46, 1307-1318 PubMed

Casanova M.F., Sokhadze E., Opris I., Wang Y., Li X. Autism spectrum disorders: Linking neuropathological findings to treatment with transcranial magnetic stimulation. Acta Paediatr. 2015 Apr 1;104, 346-355 PubMed

Werling D.M., Parikshak N.N., Geschwind D.H. Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders. Nat. Commun. 2016 Feb 19; 7, 10717 PubMed

Hutsler J.J., Casanova M.F. Review: Cortical construction in autism spectrum disorder: columns, connectivity and the subplate. Neuropathol. Appl. Neurobiol. 2016 Feb 1; 42, 115-134 PubMed

Zhang Y., Hodgson N.W., Trivedi M.S., Abdolmaleky H.M., Fournier M., Cuenod M., Do K.Q., Deth R.C. Decreased brain levels of vitamin B12 in aging, autism and schizophrenia. PLoS One 2016 Jan 22; 11, e0146797 PubMed

Crawford J.D., Chandley M.J., Szebeni K., Szebeni A., Waters B., Ordway G.A. Elevated GFAP protein in anterior cingulate cortical white matter in males with autism spectrum disorder. Autism Res. 2015 Dec 1; 8, 649-657 PubMed

Stamova B., Ander B.P., Barger N., Sharp F.R., Schumann C.M. Specific regional and age-related small noncoding RNA expression patterns within superior temporal gyrus of typical human brains are less distinct in autism brains. J. Child Neurol. 2015 Dec 1; 30, 1930-1946 PubMed

D’Gama A.M., Pochareddy S., Li M., Jamuar S.S., Reiff R.E., Lam A.T., Sestan N., Walsh C.A. Targeted DNA sequencing from autism spectrum disorder brains implicates multiple genetic mechanisms. Neuron 2015 Dec 2; 88, 910-917 PubMed

Hampson D.R., Blatt G.J. Autism spectrum disorders and neuropathology of the cerebellum. Front. Neurosci. 2015 Nov 6; 9, 420 PubMed

Wegiel J., Flory M., Schanen N.C., Cook E.H., Nowicki K., Kuchna I., Imaki H., Ma S.Y., Wegiel J., London E., Casanova M.F., Wisniewski T., Brown W.T. Significant neuronal soma volume deficit in the limbic system in subjects with 15q11.2-q13 duplications. Acta Neuropathol. Commun. 2015 Oct 13; 3, 63 PubMed

Mor M., Nardone S., Sams D.S., Elliott E. Hypomethylation of miR-142 promoter and upregulation of microRNAs that target the oxytocin receptor gene in the autism prefrontal cortex. Mol. Autism 2015 Aug 14; 6, 46 PubMed

McKavanagh R., Buckley E., Chance S.A. Wider minicolumns in autism: A neural basis for altered processing? Brain 2015 Jul 1; 138, 2034-2045 PubMed

Ander B.P., Barger N., Stamova B., Sharp F.R., Schumann C.M. Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders. Mol. Autism 2015 Jun 19; 6, 37 PubMed

Barger N., Sheley M.F., Schumann C.M. Stereological study of pyramidal neurons in the human superior temporal gyrus from childhood to adulthood. J. Comp. Neurol. 2015 May 1; 523, 1054-1072 PubMed

Hu V.W., Sarachana T., Sherrard R.M., Kocher K.M. Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism. Mol. Autism 2015 May 13; 6,7 PubMed

Kim E., Camacho J., Combs Z., Ariza J., Lechpammer M., Noctor S.C., Martínez-Cerdeño V. Preliminary findings suggest the number and volume of supragranular and infragranular pyramidal neurons are similar in the anterior superior temporal area of control subjects and subjects with autism. Neurosci. Lett. 2015 Mar 4; 589, 98-103 PubMed

Nicolini C., Ahn Y., Michalski B., Rho J.M., Fahnestock M. Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid. Acta Neuropathol. Commun. 2015 Jan 20; 3, 3 PubMed

Gupta S., Ellis S.E., Ashar F.N., Moes A., Bader J.S., Zhan J., West A.B., Arking D.E. Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism. Nat. Commun. 2014 Dec 10; 5, 5748 PubMed

Irimia M., Weatheritt R.J., Ellis J.D., Parikshak N.N., Gonatopoulos-Pournatzis T., Babor M., Quesnel-Vallières M., Tapial J., Raj B., O’Hanlon D., Barrios-Rodiles M., Sternberg M.J., Cordes S.P., Roth F.P., Wrana J.L., Geschwind D.H., Blencowe B.J. A highly conserved program of neuronal microexons is misregulated in autistic brains. Cell 2014 Dec 18; 159, 1511-1523 PubMed

Wegiel J., Flory M., Kuchna I., Nowicki K., Ma S.Y., Imaki H., Wegiel J., Cohen I.L., London E., Wisniewski T., Brown W.T. Stereological study of the neuronal number and volume of 38 brain subdivisions of subjects diagnosed with autism reveals significant alterations restricted to the striatum, amygdala and cerebellum. Acta Neuropathol. Commun. 2014 Sep 18; 2,141 PubMed

Camacho J., Ejaz E., Ariza J., Noctor S.C., Martínez-Cerdeño V. RELN-expressing neuron density in layer I of the superior temporal lobe is similar in human brains with autism and in age-matched controls. Neurosci. Lett. 2014 Sep 5; 579,163-167 PubMed

Nardone S., Sams D.S., Reuveni E., Getselter D., Oron O., Karpuj M., Elliott E. DNA methylation analysis of the autistic brain reveals multiple dysregulated biological pathways. Transl Psychiatry 2014 Sep 2; 4, e433 PubMed

Tang G., Gudsnuk K., Kuo S.H., Cotrina M.L., Rosoklija G., Sosunov A., Sonders M.S., Kanter E., Castagna C., Yamamoto A., Yue Z., Arancio O., Peterson B.S., Champagne F., Dwork A.J., Goldman J., Sulzer D. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron 2014 Sep 3; 83, 1131-1143 PubMed

Uppal N., Wicinski B., Buxbaum J.D., Heinsen H., Schmitz C., Hof P.R. Neuropathology of the anterior midcingulate cortex in young children with autism. J. Neuropathol. Exp. Neurol. 2014 Sep 1; 73, 891-902 PubMed

Smith R.M., Banks W., Hansen E., Sadee W., Herman G.E. Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder. Autism Res. 2014 Aug 1; 7, 459-4567 PubMed

Fatemi S.H., Reutiman T.J., Folsom T.D., Rustan O.G., Rooney R.J., Thuras P.D. Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism. J. Autism Dev. Disord. 2014 Aug 1; 44, 1833-1845 PubMed

Ben-David E., Shohat S., Shifman S. Allelic expression analysis in the brain suggests a role for heterogeneous insults affecting epigenetic processes in autism spectrum disorders. Hum. Mol. Genet. 2014 Aug 1; 23, 4111-4124. PubMed

Wegiel J., Flory M., Kuchna I., Nowicki K., Ma S.Y., Imaki H., Wegiel J., Cohen I.L., London E., Brown W.T., Wisniewski T. Brain-region-specific alterations of the trajectories of neuronal volume growth throughout the lifespan in autism. Acta Neuropathol. Commun. 2014 Mar 10; 2, 28 PubMed

Stoner R., Chow M.L., Boyle M.P., Sunkin S.M., Mouton P.R., Roy S., Wynshaw-Boris A., Colamarino S.A., Lein E.S., Courchesne E. Patches of disorganization in the neocortex of children with autism. N. Engl. J. Med. 2014 Mar 27; 370, 1209-1219 PubMed

Uppal N., Gianatiempo I., Wicinski B., Schmeidler J., Heinsen H., Schmitz C., Buxbaum J.D., Hof P.R. Neuropathology of the posteroinferior occipitotemporal gyrus in children with autism. Mol. Autism 2014 Feb 24; 5, 17 PubMed

Zhubi A., Chen Y., Dong E., Cook E.H., Guidotti A., Grayson D.R. Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum. Transl. Psychiatry 2014 Jan 21; 4, e349 PubMed

Edmonson C., Ziats M.N., Rennert O.M. Altered glial marker expression in autistic post-mortem prefrontal cortex and cerebellum. Mol. Autism 2014 Jan 10; 5, 3 PubMed

Zhu L., Wang X., Li X.L., Towers A., Cao X., Wang P., Bowman R., Yang H., Goldstein J., Li Y.J., Jiang Y.H. Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders. Hum. Mol. Genet. 2014 Mar 15; 23, 1563-1578 PubMed

Casanova M.F., El-Baz A.S., Kamat S.S., Dombroski B.A., Khalifa F., Elnakib A., Soliman A., Allison-McNutt A., Switala A.E. Focal cortical dysplasias in autism spectrum disorders. Acta Neuropathol. Commun. 2013 Oct 11; 1, 67 PubMed

Eran A., Li J.B., Vatalaro K., McCarthy J., Rahimov F., Collins C., Markianos K., Margulies D.M., Brown E.N., Calvo S.E., Kohane I.S., Kunkel L.M. Comparative RNA editing in autistic and neurotypical cerebella. Mol. Psychiatry 2013 Sep 1; 18, 1041-1048 PubMed

Oblak A., Gibbs T.T., Blatt G.J. Reduced serotonin receptor subtypes in a limbic and a neocortical region in autism. Autism Res. 2013 Dec 1; 6, 571-583 PubMed

Fatemi S.H., Folsom T.D., Kneeland R.E., Yousefi M.K., Liesch S.B., Thuras P.D. Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precursor protein, striatal-enriched protein tyrosine phosphatase, and homer 1, in autism: A postmortem study in cerebellar vermis and superior frontal cortex. Mol. Autism 2013 Jun 26; 4, 21 PubMed

Tang G., Gutierrez Rios P., Kuo S.H., Akman H.O., Rosoklija G., Tanji K., Dwork A., Schon E.A., Dimauro S., Goldman J., Sulzer D. Mitochondrial abnormalities in temporal lobe of autistic brain. Neurobiol. Dis. 2013 Jun 1; 54, 349-361 PubMed

Lahiri D.K., Sokol D.K., Erickson C., Ray B., Ho C.Y., Maloney B. Autism as early neurodevelopmental disorder: Evidence for an sAPPα-mediated anabolic pathway. Front. Cell Neurosci. 2013 Jun 21; 7, 94 PubMed

Vardarajan B.N., Eran A., Jung J.Y., Kunkel L.M., Wall D.P. Haplotype structure enables prioritization of common markers and candidate genes in autism spectrum disorder. Transl. Psychiatry 2013 May 28; 3, e262 PubMed

Sarachana T., Hu V.W. Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder. Mol. Autism 2013 May 22; 4, 14 PubMed

Jacot-Descombes S., Uppal N., Wicinski B., Santos M., Schmeidler J., Giannakopoulos P., Heinsen H., Schmitz C., Hof P.R. Decreased pyramidal neuron size in Brodmann areas 44 and 45 in patients with autism. Acta Neuropathol. 2012 Jul 1; 124, 67-79 PubMed

Wegiel J., Frackowiak J., Mazur-Kolecka B., Schanen N.C., Cook E.H. Jr, Sigman M., Brown W.T., Kuchna I., Wegiel J., Nowicki K., Imaki H., Ma S.Y., Chauhan A., Chauhan V., Miller D.L., Mehta P.D., Flory M., Cohen I.L., London E., Reisberg B., de Leon M.J., Wisniewski T. Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders. PLoS One 2012 Jan 1; 7, e35414 PubMed

Wegiel J., Schanen N.C., Cook E.H., Sigman M., Brown W.T., Kuchna I., Nowicki K., Wegiel J., Imaki H., Ma S.Y., Marchi E., Wierzba-Bobrowicz T., Chauhan A., Chauhan V., Cohen I.L., London E., Flory M., Lach B., Wisniewski T. Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism. J. Neuropathol. Exp. Neurol. 2012 May 1; 71, 382-397 PubMed

Wegiel J., Kuchna I., Nowicki K., Imaki H., Wegiel J., Ma S.Y., Azmitia E.C., Banerjee P., Flory M., Cohen I.L., London E., Brown W.T., Komich Hare C., Wisniewski T. Contribution of olivofloccular circuitry developmental defects to atypical gaze in autism. Brain Res. 2013 May 28; 1512, 106-122 PubMed

Chung K., Wallace J., Kim S.Y., Kalyanasundaram S., Andalman A.S., Davidson T.J., Mirzabekov J.J., Zalocusky K.A., Mattis J., Denisin A.K., Pak S., Bernstein H., Ramakrishnan C., Grosenick L., Gradinaru V., Deisseroth K. Structural and molecular interrogation of intact biological systems. Nature 2013 May 16; 497, 332-337 PubMed

Kerin T., Ramanathan A., Rivas K., Grepo N., Coetzee G.A., Campbell D.B. A noncoding RNA antisense to moesin at 5p14.1 in autism. Sci. Transl. Med. 2012 Apr 4; 4, 128ra40 PubMed

Morgan J.T., Chana G., Abramson I., Semendeferi K., Courchesne E., Everall I.P. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain Res. 2012 May 25; 1456, 72-81 PubMed

Ginsberg M.R., Rubin R.A, Natowicz M.R. Patterning of regional gene expression in autism: New complexity. Sci. Rep. 2013 Jan 1; 3,1831 PubMed

Shimmura C., Suzuki K., Iwata Y., Tsuchiya K.J., Ohno K., Matsuzaki H., Iwata K., Kameno Y., Takahashi T., Wakuda T., Nakamura K., Hashimoto K., Mori N. Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism. Mol. Autism 2013 Mar 26; 4, 6 PubMed

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